Key Information
There are theoretical mechanisms supporting the potential role of astaxanthin in the treatment of ALS, however, there are no ALS specific preclinical data exploring this treatment. One verified “ALS reversal” occurred while taking astaxanthin in the setting of a cocktail of various other therapies an association that does not prove causality. There have been no clinical trials of astaxanthin in PALS. Natural astaxanthin appears to be generally safe and inexpensive. We believe there is a need for further preclinical and/or clinical trials of natural astaxanthin in disease models and PALS, respectively, to further elucidate efficacy.